Product INN: Furaginum
Deva: 50 mg tablets
Product ATC Code: J01XE
Acute and chronic urinary tract infections: pyelonephritis, cystitis, prostatitis, urethritis; urinary postoperative infections: postoperative pyelonephritis, cystitis, prostatitis.
Product Mechanism of Action
Furagin is an antibacterial, which is active against both gram-positive (Staphylococcus epidermidis, Staphylococcus aureus, Staphylococcus faecalis), and gram-negative microorganisms (Enterobacteriaceae – Salmonella, Shygella, Proteus, Klebsiella, Escherichia, Enterobacter etc.).The preparation is effective also against those staphylococci and other pathogenic microorganisms, which are resistant to sulfanilamides and antibiotics. Resistance to furagin develops slowly and does not reach a high level. Minimal inhibitory concentration of furagin is within the limits 0.7 mg/l to 20 mg/l for treatment of infections of urinary tract.
Pseudomonas aeruginosa is resistant to furagin.
Nitrofurans suppress enzymatic systems of microorganisms, inhibiting also other biochemical processes in microorganisms’ cells followed by breakdown of their cell walls or cytoplasmic membrane.
Under nitrofurans’ effect microorganisms release less toxins, therefore the patient recovery phase can be attained sooner, before a pronounced microflora depression has occurred.
Furagin® 50 mg Tablets is used perorally after meals taken with sufficient quantity of liquid.
Adult’s dose is 100-200 mg 2-3 times a day. Treatment course duration is 7-10 days.
If necessary, the course of treatment can be repeated after 10-15 days.
Maximal dose – 600 mg daily. For the prophylaxis of chronic urinary tract infections – 50 mg daily.
Children: In case of acute infection for children older than 6 years a dose is 5-8 mg/kg of body weight per day, dividing the daily dose into 3-4 single doses. Treatment course is 7-8 days. If prolonged treatment is necessary, a dose is reduced to 1-2 mg/kg of body weight per day.
Medicines unreasonable use is harmful to health.