Product INN: Finasteridum

Deva: 5 mg coated tablets

Product ATC Code: G04CB01

Product Description

Prostarinol is 5α-reductase inhibitor used for benign prostatic hyperplasia (BPH) treatment and symptoms control:
- Acute urinary retention risk reduction;
- Reducing the need for surgery including transurethral resection of the prostate (TURP) and prostatectomy risk.
Prostarinol reduces the size of enlarged prostate, improves urine flow and relieves other symptoms of BPH (frequent urination, urgent need to urinate, difficulty in initiating urination, incomplete urine bladder emptying, partial enuresis).
Treatment with Prostarinol applies only to patients with an enlarged prostate (prostate volume greater than 40 ml).

Product Mechanism of Action

Finasteride a synthetic 4-azasteroid compound. The drug is a specific inhibitor of steroid 5α-reductase II izoenzyme type, which carries out the conversion of testosterone to 5α-dihydrotestosterone (DHT). The development and enlargement of the prostate gland is dependent on 5α-dihydrotestosterone (DHT), as a result the urethra is squeezed causing urination disorders. Inhibition of 5α-reductase by finasteride, in a dose-dependent fashion, reduces serum and prostatic DHT concentrations substantially. As a result, the enlargement of the prostate gland is reduced, urinary stream is improved and unpleasant symptoms caused by prostate gland adenoma are decreased. Natural testosterone effect on skeletal muscles and bones remains unchanged.
Decrease in DHT concentrations are observed 24 hours after finasteride administration.


It is necessary to swallow the whole tablet; it should not be divided or crushed.

The usual dosage of the preparation is 5 mg (one tablet) once daily taken with water without regard to meals.
The dose should not be adjusted in elderly patients, because the changes in pharmacokinetic characteristics are not clinically significant.
In patients with chronic renal impairment (creatinine clearance till 9-55 ml/min) – the dose adjustment is not necessary.
In patients with hepatic insufficiency - dosage information of finasteride is not available.
Prostarinol can be used alone or in combination with the alpha-blocker doxazosin.


Before use, carefully read the instructions. Consult your doctor or pharmacist about the use of medicines.
Medicines unreasonable use is harmful to health.